Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PAM | P19021 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8903497 | 0.84 | OPRM1 (0.49) | CES1CES2CYP2C19CYP1A2KMT2A | |
| SCHEMBL2291949 | 0.83 | CYP2C19 (0.47) | CYP2C19CYP1A2MEN1KMT2AHDAC8 | |
| SCHEMBL28316424 | 0.81 | CYP2C19 (0.45) | CYP2C19CYP1A2MEN1KMT2AHDAC8 | |
| SCHEMBL28875698 | 0.81 | CYP2C19 (0.45) | CYP2C19CYP1A2MEN1KMT2AHDAC8 | |
| SCHEMBL21269854 | 0.81 | CYP2C19 (0.45) | CYP2C19CYP1A2MEN1KMT2AHDAC8 | |
| SCHEMBL21268799 | 0.81 | CYP2C19 (0.45) | CYP2C19CYP1A2MEN1KMT2AHDAC8 | |
| SCHEMBL28314575 | 0.81 | CYP2C19 (0.45) | CYP2C19CYP1A2MEN1KMT2AHDAC8 | |
| SCHEMBL21269982 | 0.81 | CYP2C19 (0.45) | CYP2C19CYP1A2MEN1KMT2AHDAC8 | |
| SCHEMBL8904079 | 0.81 | CES2 (0.42) | CES1CES2CYP2C19CYP1A2DRD2 | |
| SCHEMBL28314612 | 0.80 | CYP2C19 (0.44) | CYP2C19CYP1A2MEN1KMT2AHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113913416-B | Preparation process of alcaligenes faecalis penicillin G acylase | 巢湖学院 | 2022-03-22 | — | — | CN | claimed |
| CN-113913416-A | Preparation process of alcaligenes faecalis penicillin G acylase | 巢湖学院 | 2022-01-11 | — | — | CN | claimed |
| CN-113913416-B | Preparation process of alcaligenes faecalis penicillin G acylase | 巢湖学院 | 2022-03-22 | — | — | CN | disclosed |
| CN-113913416-B | Preparation process of alcaligenes faecalis penicillin G acylase | 巢湖学院 | 2022-03-22 | — | — | CN | disclosed |
| CN-113913416-A | Preparation process of alcaligenes faecalis penicillin G acylase | 巢湖学院 | 2022-01-11 | — | — | CN | disclosed |
| CN-113913416-A | Preparation process of alcaligenes faecalis penicillin G acylase | 巢湖学院 | 2022-01-11 | — | — | CN | disclosed |