Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18130836 | 0.88 | GAA (0.39) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL18130839 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL21411461 | 0.76 | ALDH1A1 (0.62) | ALDH1A1MAPTHTTGAAKDM4E | |
| SCHEMBL3837485 | 0.76 | TAAR1 (0.33) | KMT2A | |
| SCHEMBL28549878 | 0.74 | PAX8 (0.39) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL28501406 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL28250542 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL4487969 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL28249805 | 0.72 | ALDH1A1 (0.46) | ALDH1A1MAPTHTTHPGDSMN1; SMN2 | |
| SCHEMBL2484547 | 0.71 | SMN1; SMN2 (0.59) | ALDH1A1HTTNPC1TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109562113-A | Spirocyclo-rongeur for target protein degradation | C4医药公司 | 2019-04-02 | — | — | CN | disclosed |