Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | LCK | P06239 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.49 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28872293 | 0.85 | RAB9A (0.59) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL16227041 | 0.84 | MAPT (0.68) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL16226647 | 0.84 | ALDH1A1 (0.52) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL30485987 | 0.84 | LCK (0.58) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL29709367 | 0.81 | EPHX2 (0.70) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL27909607 | 0.79 | BCL2 (0.59) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL19438103 | 0.78 | NPC1 (0.54) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL28872286 | 0.77 | EPHX2 (0.60) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL16226066 | 0.76 | RAB9A (0.64) | EPHX2MAPTLCKALDH1A1GLA | |
| SCHEMBL30020897 | 0.76 | RAB9A (0.64) | EPHX2MAPTLCKALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228095-A1 | APPLICATION OF PRISMATOMERIS CONNATA Y. Z. RUAN ROOT EXTRACT IN PREPARATION OF MEDICINE FOR TREATING PULMONARY FIBROSIS | 中国医学科学院药物研究所 | 2022-11-03 | — | — | WO | claimed |
| CN-115245533-A | Application of south mountain flower root extract in pulmonary fibrosis treatment | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | claimed |
| WO-2022228095-A1 | APPLICATION OF PRISMATOMERIS CONNATA Y. Z. RUAN ROOT EXTRACT IN PREPARATION OF MEDICINE FOR TREATING PULMONARY FIBROSIS | 中国医学科学院药物研究所 | 2022-11-03 | — | — | WO | disclosed |
| CN-115245533-A | Application of south mountain flower root extract in pulmonary fibrosis treatment | 中国医学科学院药物研究所 | 2022-10-28 | — | — | CN | disclosed |