Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 6/20 | 0.56 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.56 |
| ▸ | KDM5C | P41229 | 1/20 | 0.56 |
| ▸ | PDE9A | O76083 | 12/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22871658 | 0.76 | KDM5A (0.75) | KDM5AKDM5BKDM5CPDE9APARP1 | |
| SCHEMBL22298103 | 0.75 | KDM5A (0.69) | KDM5AKDM5BKDM5CPDE9APARP1 | |
| SCHEMBL20870262 | 0.72 | KDM5A (1.00) | KDM5AKDM5BKDM5CPDE9APARP1 | |
| SCHEMBL4754631 | 0.72 | KDM5A (0.69) | KDM5AKDM5BKDM5CPDE9APARP1 | |
| SCHEMBL14442482 | 0.72 | KDM5A (0.64) | KDM5AKDM5BKDM5CPDE9APARP1 | |
| SCHEMBL22298274 | 0.71 | PDE9A (0.62) | PDE9A | |
| SCHEMBL20870614 | 0.71 | PDE9A (0.73) | KDM5AKDM5BKDM5CPDE9APARP1 | |
| SCHEMBL20870149 | 0.71 | PDE9A (0.61) | PDE9A | |
| SCHEMBL20870339 | 0.71 | PDE9A (0.61) | KDM5AKDM5BKDM5CPDE9A | |
| SCHEMBL20870106 | 0.69 | PDE9A (1.00) | KDM5AKDM5BKDM5CPDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109575016-A | PDE9 inhibitors and uses thereof | 南京药捷安康生物科技有限公司 | 2019-04-05 | — | — | CN | disclosed |