Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 12/20 | 0.36 |
| ▸ | MEN1 | O00255 | 10/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.36 |
| ▸ | RAB9A | P51151 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 11/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29971943 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL27143654 | 0.80 | RIPK2 (0.40) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL4475058 | 0.77 | MEN1 (0.46) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL4474644 | 0.75 | NPY5R (0.44) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL4494427 | 0.74 | SMN1; SMN2 (0.44) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL4714412 | 0.73 | SMN1; SMN2 (0.54) | SMN1; SMN2MEN1KMT2ARAB9ALMNA | |
| SCHEMBL23497395 | 0.73 | PARP1 (0.36) | ALDH1A1KDM4ECYP2C19CYP1A2CYP2C9 | |
| SCHEMBL4494474 | 0.72 | ALDH1A1 (0.52) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL4482332 | 0.69 | MAPT (0.41) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8684546 | 0.67 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2ARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279747-A | Novel fYN and VEGFR2 kinase inhibitors | 罗达制药生物技术有限责任公司 | 2022-11-01 | — | — | CN | disclosed |