Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10361595 | 0.85 | TBXAS1 (0.43) | — | |
| SCHEMBL17165345 | 0.84 | HTT (0.41) | GDAPARP1 | |
| SCHEMBL11222090 | 0.83 | PDPK1 (0.32) | GDAXDH | |
| SCHEMBL6029478 | 0.82 | CASP1 (0.31) | ADORA2AADORA1 | |
| SCHEMBL766489 | 0.82 | HRH3 (0.35) | ADORA2AADORA1 | |
| SCHEMBL19746432 | 0.81 | — | — | |
| SCHEMBL7490404 | 0.81 | ADORA2A (0.43) | PDE4APDE4BPDE4CPDE4DXDH | |
| SCHEMBL2060117 | 0.81 | KDM4E (0.35) | ADORA2AADORA1 | |
| SCHEMBL4551801 | 0.79 | ADORA2A (0.44) | TLR8ADORA2AADORA1 | |
| SCHEMBL38911 | 0.79 | HRH1 (0.38) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109641015-A | By removing tri-methylated increase human somatic cell nuclear transfer (SCNT) efficiency of histone H 3-lysine, and the method and composition of increase mankind NT-ESC derivative | 儿童医疗中心有限公司 | 2019-04-16 | — | — | CN | disclosed |