Phthalazine

Phthalazine

SCHEMBL28873248

c1ccc2cnncc2c1.c1ccc2nnccc2c1.c1ccc2nnccc2c1.c1ccc2nnccc2c1.c1ccc2nnccc2c1.c1ccc2nnccc2c1

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
MAPT P10636 3/20 0.41
GLA P06280 1/20 0.41
HPGD P15428 1/20 0.41
ACHE P22303 1/20 0.41
KDM4E B2RXH2 4/20 0.38
CYP1A2 P05177 4/20 0.35
NCF1 P14598 3/20 0.35
NOS2 P35228 1/20 0.35
BACE1 P56817 1/20 0.35
CA12 O43570 1/20 0.35
CA9 Q16790 1/20 0.35
NQO2 P16083 1/20 0.34
GPR3 P46089 2/20 0.34
EGFR P00533 1/20 0.34
CYP3A4 P08684 3/20 0.34
NPC1 O15118 2/20 0.34
CYP2D6 P10635 2/20 0.34
RAB9A P51151 2/20 0.34
AR P10275 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalazine SCHEMBL4646099 1.00 ALDH1A1 (0.43) ALDH1A1MAPTGLAHPGDACHE
Naphthalene SCHEMBL28320375 0.98 ALDH1A1 (0.41) ALDH1A1MAPTGLAHPGDACHE
Cinnoline SCHEMBL8197 0.91 ALDH1A1 (0.50) ALDH1A1MAPTGLAHPGDACHE
Cinnoline SCHEMBL29367576 0.91 ALDH1A1 (0.50) ALDH1A1MAPTGLAHPGDACHE
Cinnoline SCHEMBL8589764 0.89 ALDH1A1 (0.48) ALDH1A1MAPTGLAHPGDACHE
Cinnoline SCHEMBL29388384 0.89 ALDH1A1 (0.48) ALDH1A1MAPTGLAHPGDACHE
Cinnoline SCHEMBL29733325 0.89 ALDH1A1 (0.48) ALDH1A1MAPTGLAHPGDACHE
Cinnoline SCHEMBL29184286 0.89 ALDH1A1 (0.48) ALDH1A1MAPTGLAHPGDACHE
SCHEMBL3205273 0.89 ALDH1A1 (0.48) ALDH1A1MAPTGLAHPGDACHE
Cinnoline SCHEMBL29067411 0.89 ALDH1A1 (0.48) ALDH1A1MAPTGLAHPGDACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109790150-A Substituted pyrazolinyl derivative, preparation method and its purposes as herbicide and/or plant growth regulator 拜耳作物科学股份公司 2019-05-21 CN disclosed