Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17540916 | 0.91 | HPGD (0.59) | TDP1POLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7217776 | 0.81 | HPGD (0.62) | TDP1POLBALDH1A1NPC1HPGD | |
| SCHEMBL7662082 | 0.80 | SMN1; SMN2 (0.71) | POLBALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL13685784 | 0.78 | LMNA (0.51) | TDP1POLBALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL416566 | 0.78 | TDP1 (0.91) | TDP1ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL223441 | 0.78 | TDP1 (1.00) | TDP1ALDH1A1TSHRSMN1; SMN2LMNA | |
| SCHEMBL137486 | 0.78 | TDP1 (0.83) | TDP1ALDH1A1TSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL839075 | 0.77 | TDP1 (0.75) | TDP1ALDH1A1SMN1; SMN2L3MBTL1NPC1 | |
| SCHEMBL17466182 | 0.76 | TDP1 (0.96) | TDP1ALDH1A1TSHRSMN1; SMN2NPC1 | |
| SCHEMBL2069111 | 0.76 | TDP1 (0.96) | TDP1ALDH1A1TSHRSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109721615-A | Inhibitors of influenza viruses replication and application thereof | 广东东阳光药业有限公司 | 2019-05-07 | — | — | CN | disclosed |