SCHEMBL28874153

SCHEMBL28874153

CC(C)(C)c1cccc(-c2ccccc2)c1-c1ccc(O)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 2/20 0.46
PDE4B Q07343 2/20 0.46
PDE4C Q08493 2/20 0.46
PDE4D Q08499 2/20 0.46
BCL2L1 Q07817 2/20 0.45
MMP3 P08254 1/20 0.45
CA2 P00918 1/20 0.42
ABL1 P00519 2/20 0.42
ABCB1 P08183 2/20 0.42
BCR P11274 2/20 0.42
PTPN5 P54829 1/20 0.42
ALDH1A1 P00352 3/20 0.41
TSHR P16473 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
USP7 Q93009 2/20 0.40
ESR2 Q92731 4/20 0.40
ESR1 P03372 3/20 0.39
ALOX5 P09917 1/20 0.39
CYP3A4 P08684 1/20 0.39
HNF4A P41235 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27781320 0.89 CA2 (0.41) BCL2L1CA2PTPN5ALDH1A1TSHR
Hydrogen Sulfide SCHEMBL27603612 0.88 CA2 (0.40) BCL2L1CA2PTPN5ALDH1A1TSHR
SCHEMBL6489760 0.84 CA2 (0.54) PDE4APDE4BPDE4CPDE4DBCL2L1
Phosphoric Acid SCHEMBL28381125 0.83 PTPN5 (0.51) CA2PTPN5ALDH1A1TSHRTDP1
SCHEMBL28607700 0.82 CA2 (0.52) PDE4APDE4BPDE4CPDE4DBCL2L1
SCHEMBL6839847 0.82 ALDH1A1 (0.50) BCL2L1MMP3CA2ABL1ABCB1
SCHEMBL2399392 0.82 BCL2L1 (0.61) PDE4APDE4BPDE4CPDE4DBCL2L1
SCHEMBL4651419 0.82 BCL2L1 (0.61) PDE4APDE4BPDE4CPDE4DBCL2L1
SCHEMBL2399395 0.82 BCL2L1 (0.61) PDE4APDE4BPDE4CPDE4DBCL2L1
SCHEMBL28208904 0.82 BCL2L1 (0.61) PDE4APDE4BPDE4CPDE4DBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109942362-A Include the steps that the ethylene dimerization method for handling reaction effluent IFP 新能源公司 2019-06-28 CN disclosed