Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18106186 | 0.82 | ATM (0.58) | ATMMAPK1NPSR1HSP90AA1JAK2 | |
| SCHEMBL19961477 | 0.82 | ATM (0.58) | ATMMAPK1NPSR1HSP90AA1JAK2 | |
| SCHEMBL20140554 | 0.79 | ATM (0.41) | ATMMAPK1NPSR1HSP90AA1JAK2 | |
| SCHEMBL28687006 | 0.76 | ATM (0.50) | ATMMAPK1NPSR1HSP90AA1JAK2 | |
| SCHEMBL19827172 | 0.75 | ATM (0.50) | ATMMAPK1NPSR1HSP90AA1JAK2 | |
| SCHEMBL22997901 | 0.70 | — | — | |
| SCHEMBL1756847 | 0.68 | TBXAS1 (0.40) | MAPK1L3MBTL1ALDH1A1P4HTMGAA | |
| SCHEMBL1756842 | 0.68 | TBXAS1 (0.40) | MAPK1L3MBTL1ALDH1A1P4HTMGAA | |
| SCHEMBL1124384 | 0.67 | ALDH1A1 (0.41) | MAPK1NPSR1L3MBTL1ALDH1A1P4HTM | |
| SCHEMBL1124386 | 0.67 | ALDH1A1 (0.41) | MAPK1NPSR1L3MBTL1ALDH1A1P4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124512-A | Cyclic amine derivative and medical use thereof | 东丽株式会社 | 2022-09-30 | — | — | CN | disclosed |