Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL632541 | 0.81 | PLAU (0.36) | PLAUCHRNB2CHRNA4DAOKDM4E | |
| SCHEMBL9330322 | 0.81 | DAO (0.41) | PLAUCHRNB2CHRNA4DAO | |
| SCHEMBL6664399 | 0.79 | PLAU (0.44) | PLAUDAOKDM4EPOLBRAB9A | |
| SCHEMBL9329335 | 0.79 | AXL (0.41) | PLAU | |
| SCHEMBL12139492 | 0.79 | PLAU (0.48) | PLAUCHRNB2CHRNA4DAOPOLB | |
| SCHEMBL31096826 | 0.79 | AXL (0.41) | PLAU | |
| Hydrochloric Acid SCHEMBL10639856 | 0.77 | AXL (0.39) | PLAU | |
| SCHEMBL24528250 | 0.75 | — | — | |
| SCHEMBL10858069 | 0.75 | HPGD (0.41) | PLAUCHRNB2CHRNA4KDM4EPOLB | |
| SCHEMBL9455811 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115252591-A | Application of DMDD in preparation of anti-breast cancer drugs and cancer targeted drug prepared from DMDD | 广西医科大学 | 2022-11-01 | — | — | CN | disclosed |