SCHEMBL632541

SCHEMBL632541

Cc1ncc(Cl)c(Cl)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.36
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
DAO P14920 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12139492 0.81 PLAU (0.48) PLAUPOLBCHRNB2CHRNA4DAO
SCHEMBL28874208 0.81 PLAU (0.44) PLAUKDM4EPOLBRAB9ASMN1; SMN2
SCHEMBL9455975 0.78 AXL (0.42) CYP3A4
SCHEMBL10858069 0.77 HPGD (0.41) PLAUKDM4EPOLBRAB9ASMN1; SMN2
SCHEMBL17682380 0.77 PLAU (0.33) PLAUCHRNB2CHRNA4
SCHEMBL17670982 0.77 PLAU (0.37) PLAUKDM4ECHRNB2CHRNA4RXFP1
SCHEMBL8122034 0.74 VRK1 (0.34) SMN1; SMN2DAO
SCHEMBL10861616 0.74 CYP3A4 (0.33) PLAUKDM4ECYP3A4
SCHEMBL9330322 0.72 DAO (0.41) PLAUCHRNB2CHRNA4DAO
SCHEMBL23611668 0.72 PLAU (0.34) PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115702132-A Composition for enhancing nitrogen stabilizers, method and use thereof 沃戴申生命科学美国有限责任公司 2023-02-14 CN claimed
CN-115397244-A Nitrification inhibitor fungicide composition and use thereof 沃戴申生命科学美国有限责任公司 2022-11-25 CN claimed
CN-114804481-A Treatment method of pyridine-containing wastewater 山东潍坊润丰化工股份有限公司 2022-07-29 CN claimed
CN-110514766-B Method for determining trichloromethylpyridine in food 中国检验检疫科学研究院 2022-03-01 CN claimed
CN-113056453-A Trichloromethylpyridine compositions for enhanced nitrogen utilization and improved plant growth 美国维德赛生命科学有限公司 2021-06-29 CN claimed
CN-107108383-B Nitrification inhibitor composition and process for preparing same 美国陶氏益农公司 2021-05-25 CN claimed
CN-111902042-A Production method of sugarcane transplanting unit 先正达参股股份有限公司 2020-11-06 CN claimed
CN-115702132-B Composition for enhancing nitrogen stabilizer, method and use thereof 沃戴申生命科学美国有限责任公司 2025-02-21 CN disclosed
CN-119403445-A Fungicidal compositions 先正达农作物保护股份公司 2025-02-07 CN disclosed
CN-119095487-A Fungicidal compositions 先正达农作物保护股份公司 2024-12-06 CN disclosed
CN-118434283-A Fungicidal compositions 先正达农作物保护股份公司 2024-08-02 CN disclosed
CN-110637082-B Bacillus isolates and uses thereof 诺维信生物农业公司 2024-04-05 CN disclosed
CN-117715520-A Compositions and methods for improving the rain tolerance of proteins on plant surfaces 诺维信公司 2024-03-15 CN disclosed
US-20120148661-A1 HIGH BIOAVAILABILITY ORAL PICOPLATIN ANTI-CANCER THERAPY PONIARD PHARMACEUTICALS, INC. (US) 2012-06-14 US disclosed
EP-2418955-A1 HIGH BIOAVAILABILITY ORAL PICOPLATIN ANTI-CANCER THERAPY Poniard Pharmaceuticals, Inc. (US) 2012-02-22 EP disclosed
WO-2010120336-A1 HIGH BIOAVAILABILITY ORAL PICOPLATIN ANTI-CANCER THERAPY PONIARD PHARMACEUTICALS, INC. (US) 2010-10-21 WO disclosed
US-20100062056-A1 ENCAPSULATED PICOPLATIN PONIARD PHARMACEUTICALS, INC. (US) 2010-03-11 US disclosed
EP-2109451-A1 ENCAPSULATED PICOPLATIN Poniard Pharmaceuticals, Inc. (US) 2009-10-21 EP disclosed
WO-2008097658-A1 ENCAPSULATED PICOPLATIN PONIARD PHARMACEUTICALS, INC. (US) 2008-08-14 WO disclosed
US-4594422-A Hydroxylation of a 6-halo picolinic acid with a aqueous mineral acid solution; then halogenating THE DOW CHEMICAL COMPANY (US) 1986-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100062056-A1 ENCAPSULATED PICOPLATIN PDCD2L, STOM, SLC46A1 PLAU 2470/4885KDM4E 4851/4885POLB 1447/4885
US-20120148661-A1 HIGH BIOAVAILABILITY ORAL PICOPLATIN ANTI-CANCER THERAPY PPIF, SLC30A5, SLC40A1 PLAU 2734/4885KDM4E 3948/4885POLB 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.