Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31096826 | 1.00 | AXL (0.41) | AXLPRKCICCR1CCR5CCR8 | |
| Hydrochloric Acid SCHEMBL10639856 | 0.97 | AXL (0.39) | AXLPRKCICCR1CCR5CCR8 | |
| SCHEMBL9455975 | 0.81 | AXL (0.42) | AXLPRKCICCR1CCR5CCR8 | |
| SCHEMBL23743789 | 0.79 | CCR1 (0.41) | AXLPRKCICCR1CCR5CCR8 | |
| SCHEMBL28874208 | 0.79 | PLAU (0.44) | PLAU | |
| SCHEMBL24528250 | 0.75 | — | — | |
| SCHEMBL9455811 | 0.75 | — | — | |
| SCHEMBL874915 | 0.75 | CCR1 (0.46) | CCR1CCR5CCR8NOS3NOS2 | |
| SCHEMBL20285921 | 0.73 | LMNA (0.32) | — | |
| Water SCHEMBL28540792 | 0.72 | CCR1 (0.44) | CCR1CCR5CCR8NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226558-B1 | Chemical intermediates and methods for their preparation | HAESSLE AB (SE) | 1994-04-06 | — | — | EP | claimed |
| EP-0226558-A2 | Chemical intermediates and methods for their preparation | Aktiebolaget Hässle (SE) | 1987-06-24 | — | — | EP | claimed |
| EP-3801484-A1 | BIO-BASED MEDICINES AND METHODS OF INCREASING PATIENT COMPLIANCE | Anellotech, Inc. (US) | 2021-04-14 | — | — | EP | disclosed |
| US-20180170948-A1 | COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | Bio TheryX, Inc. | 2018-06-21 | — | — | US | disclosed |
| US-20070185064-A1 | 2-Aminopurine Analogs Having HSP90-Inhibiting Activity | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-08-09 | — | — | US | disclosed |
| US-20070185064-A1 | 2-Aminopurine Analogs Having HSP90-Inhibiting Activity | CONFORMA THERAPEUTICS CORPORATION (US) | 2007-08-09 | — | — | US | disclosed |
| EP-0226558-B1 | Chemical intermediates and methods for their preparation | HAESSLE AB (SE) | 1994-04-06 | — | — | EP | disclosed |
| EP-0484265-A1 | A process for the preparation of omeprazol | CENTRO GENESIS PARA LA INVESTIGACION, S.L. (ES) | 1992-05-06 | — | — | EP | disclosed |
| US-4785113-A | 2,4-dichloro-3,5,6-trimethylpyridine | AKTIEBOLAGET HASSLE (SE) | 1988-11-15 | — | — | US | disclosed |
| EP-0226558-A2 | Chemical intermediates and methods for their preparation | Aktiebolaget Hässle (SE) | 1987-06-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180170948-A1 | COMPOUNDS TARGETING PROTEINS, COMPOSITIONS, METHODS, AND USES THEREOF | CKS1B, IKZF3, EPAS1 | AXL 651/4885PRKCI 192/4885CCR1 233/4885 |
| US-20070185064-A1 | 2-Aminopurine Analogs Having HSP90-Inhibiting Activity | HSP90AB2P, HSP90AB1, HSP90AA1 | AXL 4732/4885PRKCI 2672/4885CCR1 4568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.