Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 5/20 | 0.40 |
| ▸ | JAK1 | P23458 | 5/20 | 0.40 |
| ▸ | TYK2 | P29597 | 5/20 | 0.40 |
| ▸ | JAK3 | P52333 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28874800 | 0.90 | SMN1; SMN2 (0.44) | NPC1RAB9ALMNAJAK2JAK1 | |
| SCHEMBL28874832 | 0.86 | MAPT (0.45) | MAPTNPC1RAB9ACASP3SENP8 | |
| SCHEMBL30040330 | 0.84 | FOS (0.46) | MAPTNPC1RAB9ACASP3SENP8 | |
| SCHEMBL28874806 | 0.84 | FOS (0.46) | MAPTNPC1RAB9ACASP3SENP8 | |
| SCHEMBL24596386 | 0.80 | TAS2R14 (0.52) | MAPTLMNAJAK2SYKPTK2 | |
| SCHEMBL29789888 | 0.80 | TAS2R14 (0.52) | MAPTLMNAJAK2SYKPTK2 | |
| SCHEMBL28874816 | 0.74 | FOS (0.57) | MAPTNPC1RAB9ACASP3SENP8 | |
| SCHEMBL24596338 | 0.73 | MAPT (0.41) | MAPTNPC1RAB9ACASP3SENP8 | |
| SCHEMBL24596387 | 0.73 | MAPT (0.41) | MAPTNPC1RAB9ACASP3SENP8 | |
| SCHEMBL29789936 | 0.73 | MAPT (0.41) | MAPTNPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260187-A | Pyridone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-11-01 | — | — | CN | disclosed |