Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | BCL3 | P20749 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29061013 | 0.82 | MEN1 (0.49) | ALDH1A1PKMRXFP1POLBHSD17B10 | |
| SCHEMBL27368366 | 0.80 | GAA (0.57) | SLC6A2SLC6A4ALDH1A1POLBHSD17B10 | |
| SCHEMBL28874951 | 0.75 | BCL3 (0.56) | BCL3SLC6A2SLC6A4ALDH1A1POLB | |
| SCHEMBL3764748 | 0.73 | SSTR4 (0.43) | SLC6A2SLC6A4ALDH1A1POLBHSD17B10 | |
| SCHEMBL27948473 | 0.71 | SSTR4 (0.42) | ALDH1A1MEN1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL1662863 | 0.69 | SSTR4 (0.41) | SLC6A2SLC6A4ALDH1A1POLBHSD17B10 | |
| SCHEMBL3761621 | 0.69 | POLB (0.41) | TP53SLC6A2SLC6A4POLBL3MBTL1 | |
| SCHEMBL27978405 | 0.69 | SLC6A2 (0.41) | SLC6A2SLC6A4POLBHSD17B10L3MBTL1 | |
| SCHEMBL28115345 | 0.69 | ALDH1A1 (0.48) | SLC6A2SLC6A4ALDH1A1MEN1LMNA | |
| SCHEMBL28001409 | 0.68 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016003-A | 2- benzene carbon amide yl-benzamide derivatives as Bcl-3 inhibitor | 卡迪夫大学学院顾问有限公司 | 2019-07-16 | — | — | CN | claimed |
| CN-110016003-A | 2- benzene carbon amide yl-benzamide derivatives as Bcl-3 inhibitor | 卡迪夫大学学院顾问有限公司 | 2019-07-16 | — | — | CN | disclosed |