Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551053 | 0.75 | DHFR (0.45) | HSP90AA1DHFRPKMNUDT1L3MBTL1 | |
| SCHEMBL28150295 | 0.73 | DHFR (0.44) | HSP90AA1DHFRPKMNUDT1 | |
| SCHEMBL15579444 | 0.72 | DHFR (0.43) | HSP90AA1DHFRPKMNUDT1L3MBTL1 | |
| SCHEMBL28236618 | 0.72 | DHFR (0.47) | DHFRPKMNUDT1 | |
| SCHEMBL28762999 | 0.71 | HSP90AA1 (0.56) | HSP90AA1DHFRNUDT1L3MBTL1 | |
| SCHEMBL28770973 | 0.67 | TLR8 (0.53) | DHFR | |
| SCHEMBL27523630 | 0.67 | DHFR (0.48) | DHFR | |
| SCHEMBL9284521 | 0.66 | PKM (0.42) | DHFRPKM | |
| SCHEMBL1554275 | 0.65 | PKM (0.55) | DHFRPKM | |
| SCHEMBL29352921 | 0.65 | PKM (0.55) | DHFRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260234-A | 2-amino-4-amino aryl phospho-oxypyrimidine compound and preparation method and application thereof | 江苏医药职业学院 | 2022-11-01 | — | — | CN | disclosed |