SCHEMBL28875302

SCHEMBL28875302

CC(C)(C)[Si](C)(C)OC1CCc2cc(OB(O)O)ccc2C1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
ACHE P22303 2/20 0.36
CYP1A2 P05177 2/20 0.34
CYP11B1 P15538 2/20 0.34
CYP11B2 P19099 2/20 0.34
CYP26A1 O43174 1/20 0.34
CYP19A1 P11511 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2B6 P20813 1/20 0.34
DRD2 P14416 2/20 0.33
DRD3 P35462 2/20 0.33
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
FAAH O00519 8/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30082721 0.84 CA1 (0.32) CA1CA2ACHECYP1A2CYP11B1
SCHEMBL23364899 0.82 CYP1A2 (0.35) CA1CA2ACHECYP1A2CYP11B1
SCHEMBL23364990 0.82 CYP2C9 (0.40) CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9
SCHEMBL29113480 0.78 CYP1A2 (0.37) ACHECYP1A2CYP11B1CYP11B2CYP3A4
SCHEMBL30612410 0.78 CYP1A2 (0.37) ACHECYP1A2CYP11B1CYP11B2CYP3A4
SCHEMBL3806985 0.76 PLAU (0.41) CA1CA2CYP19A1MTNR1AMTNR1B
SCHEMBL356130 0.74 DRD2 (0.55) CA1CA2ACHEDRD2DRD3
SCHEMBL29851851 0.74 CYP1A2 (0.33) CYP1A2CYP11B1CYP11B2CYP3A4CYP2C9
SCHEMBL14812350 0.71 DRD2 (0.51) CA1CA2ACHECYP1A2CYP11B1
SCHEMBL354259 0.70 MTNR1A (0.39) CA1CA2ACHEMTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115297930-A Antimicrobial compounds and methods 库扎环球有限责任公司 2022-11-04 CN disclosed