Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953320 | 0.76 | CYP1A2 (0.51) | RAB9AUSP2CYP1A2KMT2ACTBP2 | |
| SCHEMBL8953325 | 0.76 | CYP1A2 (0.51) | RAB9AUSP2CYP1A2KMT2ACTBP2 | |
| SCHEMBL12802274 | 0.76 | CYP1A2 (0.54) | USP2CYP1A2GRM2GRM3KMT2A | |
| SCHEMBL7495740 | 0.74 | TAAR1 (0.43) | ABCB1HTR1ADRD2KMT2AMEN1 | |
| SCHEMBL2036352 | 0.73 | BLM (0.55) | USP2CYP1A2GRM2GRM3KMT2A | |
| SCHEMBL2036351 | 0.73 | BLM (0.55) | USP2CYP1A2GRM2GRM3KMT2A | |
| SCHEMBL29499675 | 0.73 | BLM (0.55) | USP2CYP1A2GRM2GRM3KMT2A | |
| SCHEMBL27633072 | 0.73 | ABCB1 (0.53) | ABCB1HTR1ADRD2KMT2AMEN1 | |
| SCHEMBL21602082 | 0.72 | CYP1A2 (0.52) | USP2CYP1A2GRM2GRM3KMT2A | |
| SCHEMBL28085847 | 0.72 | CYP1A2 (0.52) | USP2CYP1A2GRM2GRM3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | MSD K.K. (JP) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100121069-A1 | METHOD FOR MANUFACTURING A BETA-DIARYL ELECTRON WITHDRAWING GROUP SUBSTITUTED COMPOUND | BMP6, GPR6, ACSL6 | RAB9A 3234/4885USP2 4570/4885ABCB1 2594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.