Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9231926 | 0.75 | ABCB1 (0.39) | TAAR1ABCB1HTR1ADRD2IDO1 | |
| SCHEMBL2887535 | 0.74 | RAB9A (0.45) | ABCB1HTR1ADRD2MEN1KMT2A | |
| SCHEMBL27633072 | 0.74 | ABCB1 (0.53) | ABCB1HTR1ADRD2MEN1KMT2A | |
| SCHEMBL809219 | 0.73 | TAAR1 (0.53) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL30183964 | 0.73 | TAAR1 (0.53) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL8325279 | 0.73 | TAAR1 (0.53) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL24177286 | 0.70 | TAAR1 (0.54) | TAAR1IDO1AGXTMAOBMEN1 | |
| SCHEMBL22458119 | 0.70 | TAAR1 (0.54) | TAAR1IDO1AGXTMAOBMEN1 | |
| SCHEMBL73635 | 0.69 | TAAR1 (0.56) | TAAR1IDO1AGXTMAOB | |
| SCHEMBL8953320 | 0.69 | CYP1A2 (0.51) | MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934937-B1 | Azole derivatives as superoxide radical inhibitor | OTSUKA PHARMA CO LTD (JP) | 2002-02-27 | — | — | EP | disclosed |