Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Riboflavin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 1/20 | 0.75 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.75 |
| ▸ | MEN1 | O00255 | 7/20 | 0.89 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.89 |
| ▸ | USP2 | O75604 | 4/20 | 0.89 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.89 |
| ▸ | HAT1 | O14929 | 4/20 | 0.89 |
| ▸ | RBBP7 | Q16576 | 4/20 | 0.89 |
| ▸ | HTT | P42858 | 4/20 | 0.89 |
| ▸ | RECQL | P46063 | 3/20 | 0.89 |
| ▸ | CASP7 | P55210 | 3/20 | 0.89 |
| ▸ | MAPT | P10636 | 3/20 | 0.89 |
| ▸ | CASP1 | P29466 | 2/20 | 0.89 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.89 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.89 |
| ▸ | TST | Q16762 | 2/20 | 0.89 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.89 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.89 |
| ▸ | LMNA | P02545 | 1/20 | 0.89 |
| ▸ | HBB | P68871 | 1/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Riboflavin SCHEMBL20528621 | 0.99 | MEN1 (0.90) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL27796272 | 0.98 | MEN1 (0.89) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL50096 | 0.98 | MEN1 (0.92) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL22034360 | 0.98 | MEN1 (0.92) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL826819 | 0.98 | MEN1 (0.92) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL20474794 | 0.97 | MEN1 (0.90) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL2241200 | 0.97 | MEN1 (0.90) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL27628044 | 0.97 | MEN1 (0.90) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL4922293 | 0.95 | MEN1 (0.98) | MEN1KMT2AUSP2KDM4EHAT1 | |
| Riboflavin SCHEMBL4380877 | 0.95 | MEN1 (0.98) | MEN1KMT2AUSP2KDM4EHAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105235-A | A kind of preparation method of high-purity sodium pantothenate | 珠海润都制药股份有限公司 | 2019-08-09 | — | — | CN | disclosed |