Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | FYN | P06241 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | VCP | P55072 | 2/20 | 0.44 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137308 | 0.89 | KMO (0.63) | KMOFAAHMAP4K4SMN1; SMN2 | |
| SCHEMBL19933676 | 0.89 | MEN1 (0.52) | KMOMEN1KMT2AMAPTNTSR1 | |
| SCHEMBL19244911 | 0.84 | KMO (0.46) | KMOMEN1KMT2AMAPTNTSR1 | |
| SCHEMBL28314105 | 0.82 | KMO (0.61) | KMOMEN1KMT2AMAPTFAAH | |
| SCHEMBL25295702 | 0.80 | CYP1A2 (0.60) | KMOMEN1KMT2AMAPTFAAH | |
| SCHEMBL20137329 | 0.80 | CYP1A2 (0.60) | KMOMEN1KMT2AMAPTFAAH | |
| SCHEMBL1257940 | 0.79 | KMO (0.58) | KMOMEN1KMT2AMAPTFAAH | |
| SCHEMBL21228520 | 0.76 | MAPT (0.56) | KMOMEN1KMT2AMAPTFYN | |
| SCHEMBL6845003 | 0.76 | KMO (0.54) | KMOMAPTFAAHMAP4K4MAPK1 | |
| SCHEMBL559244 | 0.76 | KMO (0.68) | KMOMEN1KMT2AMAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110049974-A | The purposes of pyrimidone derivatives and its bioactivity for neutralizing chemotactic factor (CF) | 国家科学研究中心 | 2019-07-23 | — | — | CN | disclosed |