Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 8/20 | 0.63 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | SMO | Q99835 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20137329 | 0.89 | CYP1A2 (0.60) | KMOFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25295702 | 0.89 | CYP1A2 (0.60) | KMOFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28875604 | 0.89 | KMO (0.59) | KMOFAAHSMN1; SMN2MAP4K4 | |
| SCHEMBL1257940 | 0.89 | KMO (0.58) | KMOFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6845003 | 0.85 | KMO (0.54) | KMOFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL559244 | 0.85 | KMO (0.68) | KMOFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10272930 | 0.80 | KMO (0.50) | KMOFAAHNPC1RAB9ANOTUM | |
| SCHEMBL20816288 | 0.80 | FAAH (0.51) | KMOFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10220591 | 0.80 | KMO (0.50) | KMOFAAHNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4844440 | 0.80 | FAAH (0.51) | KMOFAAHSMN1; SMN2ASIC3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226065-A1 | USE OF RAGE INHIBITORS TO TREAT CANCER-RELATED COGNITIVE DECLINE | GEORGETOWN UNIVERSITY (US) | 2024-07-11 | — | — | US | disclosed |
| EP-4337318-A1 | USE OF RAGE INHIBITORS TO TREAT CANCER-RELATED COGNITIVE DECLINE | GEORGETOWN UNIVERSITY (US) | 2024-03-20 | — | — | EP | disclosed |
| WO-2022240970-A1 | USE OF RAGE INHIBITORS TO TREAT CANCER-RELATED COGNITIVE DECLINE | GEORGETOWN UNIVERSITY (US) | 2022-11-17 | — | — | WO | disclosed |
| CN-114284447-A | Organic compound, light-emitting element, and method for synthesizing organic compound | 株式会社半导体能源研究所 | 2022-04-05 | — | — | CN | disclosed |
| EP-3507294-B1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-02-24 | — | — | EP | disclosed |
| US-10889604-B2 | Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices | MERCK PATENT GMBH | 2021-01-12 | — | — | US | disclosed |
| US-10749112-B2 | Light-emitting element, display device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| US-10749112-B2 | Light-emitting element, display device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2020-08-18 | — | — | US | disclosed |
| US-20190245146-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2019-08-08 | — | — | US | disclosed |
| US-20190245146-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2019-08-08 | — | — | US | disclosed |
| US-20190202851-A1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-07-04 | — | — | US | disclosed |
| US-10270039-B2 | Light-emitting element, display device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2019-04-23 | — | — | US | disclosed |
| US-10270039-B2 | Light-emitting element, display device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2019-04-23 | — | — | US | disclosed |
| US-20180138416-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-05-17 | — | — | US | disclosed |
| US-20180138416-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-05-17 | — | — | US | disclosed |
| US-20180138416-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190202851-A1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | PARN, PUF60, PARG | KMO 1987/4885FAAH 4774/4885NPC1 4603/4885 |
| US-10889604-B2 | Binuclear and trinuclear metal complexes composed of two inter-linked tripodal hexadentate ligands for use in electroluminescent devices | PARN, PUF60, PARG | KMO 1987/4885FAAH 4774/4885NPC1 4603/4885 |
| US-20180138416-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | ESR1, EHD1, PPOX | KMO 1042/4885FAAH 2612/4885NPC1 3525/4885 |
| US-10270039-B2 | Light-emitting element, display device, electronic device, and lighting device | ESR1, EHD1, PPOX | KMO 1042/4885FAAH 2612/4885NPC1 3525/4885 |
| US-20190245146-A1 | Light-Emitting Element, Display Device, Electronic Device, and Lighting Device | ESR1, EHD1, PPOX | KMO 1042/4885FAAH 2612/4885NPC1 3525/4885 |
| US-10749112-B2 | Light-emitting element, display device, electronic device, and lighting device | ESR1, EHD1, PPOX | KMO 1042/4885FAAH 2612/4885NPC1 3525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.