Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2284288 | 0.80 | BRD4 (0.54) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL12890135 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL22210774 | 0.76 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL18256948 | 0.76 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL27972868 | 0.76 | MAPT (0.45) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL28966300 | 0.75 | ALDH1A1 (0.59) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL20524639 | 0.75 | PTGS2 (0.51) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL1136978 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL31186124 | 0.73 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATSHRCFTR | |
| SCHEMBL21246033 | 0.73 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNATSHRCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041316-A | TAM family kinase/and CSF1R kinase inhibitor and application thereof | 南京药捷安康生物科技有限公司 | 2019-07-23 | — | — | CN | disclosed |