Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 8/20 | 0.35 |
| ▸ | KLK1 | P06870 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2889819 | 0.93 | KLKB1 (0.36) | KLKB1KLK1HPGDGRIA2SMN1; SMN2 | |
| SCHEMBL2889773 | 0.89 | KLKB1 (0.36) | KLKB1KLK1HPGDGRIA2SMN1; SMN2 | |
| SCHEMBL1832574 | 0.87 | TSHR (0.36) | KLKB1KLK1HPGDMAPT | |
| SCHEMBL2884044 | 0.86 | HPGD (0.36) | KLKB1KLK1HPGDSMN1; SMN2GAA | |
| SCHEMBL13335219 | 0.86 | KLKB1 (0.38) | KLKB1KLK1HPGDGRIA2SMN1; SMN2 | |
| SCHEMBL2889777 | 0.85 | KLKB1 (0.35) | KLKB1KLK1HPGDGRIA2SMN1; SMN2 | |
| SCHEMBL2891971 | 0.83 | KLKB1 (0.37) | KLKB1KLK1HPGDGRIA2SMN1; SMN2 | |
| SCHEMBL2892372 | 0.83 | CYP1A2 (0.41) | KLKB1KLK1HPGDGRIA2SMN1; SMN2 | |
| SCHEMBL2891612 | 0.83 | KLKB1 (0.39) | KLKB1KLK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL1831916 | 0.81 | KLKB1 (0.45) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2010-05-27 | — | — | US | disclosed |
| US-7674807-B2 | Heterocycle-substituted n-phenyl-phthalamide derivatives, related compounds and their use as insecticides | BAYER CROPSCIENCE AG (DE) | 2010-03-09 | — | — | US | disclosed |
| EP-1727804-B1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-04 | — | — | EP | disclosed |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130743-A1 | HETEROCYCLE-SUBSTITUTED, N-PHENYL-PHTHALAMIDE DERIVATIVES, RELATED COMPOUNDS AND THEIR USE AS INSECTICIDES | DDT, SQOR, CYP2S1 | KLKB1 4851/4885KLK1 3915/4885HPGD 1285/4885 |
| US-20070299085-A1 | N1-((Pyrazol-1-Ymethyl)-2-Methylphenyl)-Phatalamide Derivatives And Related Compounds Insecticides | CHRM1, KCNH1, DDT | KLKB1 4628/4885KLK1 3613/4885HPGD 1979/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.