Malonic Acid

Malonic Acid

SCHEMBL28875949

CC.CC(C)[Na].O=C(O)CC(=O)O

nearest known ligand 0.56

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.56
SRR Q9GZT4 1/20 0.56
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
PTGS2 P35354 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
FFAR3 O14843 1/20 0.37
GABRP O00591 2/20 0.36
GABRD O14764 2/20 0.36
GABRA1 P14867 2/20 0.36
GABRB1 P18505 2/20 0.36
GABRG2 P18507 2/20 0.36
GABRB3 P28472 2/20 0.36
GABRA5 P31644 2/20 0.36
GABRA3 P34903 2/20 0.36
GABRA2 P47869 2/20 0.36
GABRB2 P47870 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL3608474 0.83
Malonic Acid SCHEMBL28314619 0.82 LDHA (0.50) LDHASRRCYP2D6CYP2C19ALDH1A1
Malonic Acid SCHEMBL22499636 0.80 LDHA (0.64) LDHASRRCYP2D6CYP2C19ALDH1A1
Malonic Acid SCHEMBL30288562 0.80 LDHA (0.64) LDHASRRCYP2D6CYP2C19ALDH1A1
Malonic Acid SCHEMBL27964676 0.80 LDHA (0.64) LDHASRRCYP2D6CYP2C19ALDH1A1
Malonic Acid SCHEMBL7756791 0.79
Malonic Acid SCHEMBL27964971 0.78 LDHA (0.60) LDHASRRCYP2D6CYP2C19ALDH1A1
Malonic Acid SCHEMBL782125 0.75
Bicarbonate SCHEMBL29280588 0.75
Malonic Acid SCHEMBL1332587 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110172019-A The metal salt of malonic acid as the nucleating additive for crystalline thermoplastic 印度石油有限公司 2019-08-27 CN claimed