Malonic Acid

Malonic Acid

SCHEMBL7756791

C[Na].O=C(O)CC(=O)O

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL782125 0.87
Malonic Acid SCHEMBL3608474 0.87
Malonic Acid SCHEMBL23831 0.87 LDHA (1.00)
Malonic Acid SCHEMBL336 0.87
Malonic Acid SCHEMBL28221810 0.87 LDHA (1.00)
Malonic Acid SCHEMBL1332405 0.87
Malonic Acid SCHEMBL1332554 0.87
Malonic Acid SCHEMBL1332587 0.87
Malonic Acid SCHEMBL3358611 0.87
Malonic Acid SCHEMBL9635789 0.85 LDHA (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220259146-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAEWOONG PHARMACEUTICAL CO LTD (KR) 2022-08-18 US claimed
US-11345660-B2 Method for preparing intermediate of 4-methoxypyrrole derivative DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2022-05-31 US claimed
EP-3642181-B1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAE WOONG PHARMA (KR) 2021-11-03 EP claimed
US-20200181080-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2020-06-11 US claimed
EP-3642181-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE Daewoong Pharmaceutical Co., Ltd. (KR) 2020-04-29 EP claimed
WO-2018236153-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2018-12-27 WO claimed
US-20220259146-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAEWOONG PHARMACEUTICAL CO LTD (KR) 2022-08-18 US disclosed
US-11345660-B2 Method for preparing intermediate of 4-methoxypyrrole derivative DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2022-05-31 US disclosed
EP-3642181-B1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAE WOONG PHARMA (KR) 2021-11-03 EP disclosed
US-20200181080-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2020-06-11 US disclosed
EP-3642181-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE Daewoong Pharmaceutical Co., Ltd. (KR) 2020-04-29 EP disclosed
WO-2018236153-A1 METHOD FOR PREPARING INTERMEDIATE OF 4-METHOXYPYRROLE DERIVATIVE DAEWOONG PHARMACEUTICAL CO., LTD. (KR) 2018-12-27 WO disclosed
EP-1091927-A1 PROCESS FOR PREPARATION OF SUBSTITUTED PROPENOIC ACID ESTERS Vyas, Sharad Kumar (IN) 2001-04-18 EP disclosed
US-4299773-A Ester derivatives of polycarboxylic acids and process for making same LEVER BROTHERS COMPANY (US) 1981-11-10 US disclosed
US-4275007-A β-Lactone esters LEVER BROTHERS COMPANY (US) 1981-06-23 US disclosed
US-4273935-A Salts of propene 1,1,2,3-tetracarboxylic acid LEVER BROTHERS COMPANY (US) 1981-06-16 US disclosed
US-4218381-A Novel ester derivatives of polycarboxylic acids and process for making same LEVER BROTHERS COMPANY (US) 1980-08-19 US disclosed
US-4209636-A Preparation of ester derivatives of polycarboxylic acids LEVER BROTHERS COMPANY (US) 1980-06-24 US disclosed
US-4159388-A Ester derivatives of 1-halo-1,1,2,3-propane tetracarboxylic acid LEVER BROTHERS COMPANY (US) 1979-06-26 US disclosed
US-4123458-A HALOGENATION, DEHYDROGENATION, DECARBOXYLATION LEVER BROTHERS COMPANY (US) 1978-10-31 US disclosed