Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23388919 | 0.88 | USP2 (0.41) | USP2SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL27472535 | 0.74 | PDE4A (0.36) | MAPK1KDM4EMAPTTHRBHRH3 | |
| SCHEMBL17667653 | 0.73 | — | — | |
| SCHEMBL29152566 | 0.71 | MAPK1 (0.41) | USP2SMN1; SMN2MAPK1KDM4EMAPT | |
| SCHEMBL7383427 | 0.65 | MAPK1 (0.41) | SMN1; SMN2MAPK1 | |
| SCHEMBL17667648 | 0.65 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL28876266 | 0.64 | USP2 (0.33) | USP2SMN1; SMN2 | |
| SCHEMBL7146602 | 0.63 | L3MBTL1 (0.37) | SMN1; SMN2MAPTHRH3 | |
| SCHEMBL1563999 | 0.63 | USP2 (0.49) | USP2SMN1; SMN2RECQL | |
| SCHEMBL28389874 | 0.63 | USP2 (0.41) | USP2SMN1; SMN2KDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279368-B | Heteroaryl compounds | 维瓦斯治疗公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115279368-A | Heteroaryl compounds | 维瓦斯治疗公司 | 2022-11-01 | — | — | CN | disclosed |