Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 7/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1701326 | 0.96 | HPGD (0.46) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| Urea SCHEMBL9252216 | 0.86 | HPGD (0.40) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL17415975 | 0.83 | HPGD (0.43) | HPGDACHECA12CA1CA2 | |
| SCHEMBL28673557 | 0.83 | CA12 (0.43) | ACHEALDH1A1CA12CA1CA2 | |
| SCHEMBL28160030 | 0.81 | CA12 (0.52) | ACHECA12CA1CA2CA9 | |
| SCHEMBL11203544 | 0.81 | ACHE (0.44) | HPGDACHECA12CA1CA2 | |
| SCHEMBL4349098 | 0.79 | — | — | |
| SCHEMBL4349103 | 0.79 | — | — | |
| SCHEMBL27612180 | 0.77 | HPGD (0.37) | HPGDCHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL7322366 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110114456-A | Novel acyltransferase, variant thioesterase and its purposes | 柯碧恩生物技术公司 | 2019-08-09 | — | — | CN | disclosed |