Urea

Urea

SCHEMBL9252216

CCCNC(=S)OCCC.NC(N)=O

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.40
ACHE P22303 8/20 0.37
CHRNB2 P17787 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA4 P43681 1/20 0.37
ALDH1A1 P00352 3/20 0.36
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MMP1 P03956 1/20 0.35
MMP2 P08253 1/20 0.35
MMP3 P08254 1/20 0.35
MMP9 P14780 1/20 0.35
EPHX1 P07099 1/20 0.34
MEN1 O00255 2/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1701326 0.90 HPGD (0.46) HPGDACHECHRNB2CHRNB4CHRNA3
SCHEMBL27612180 0.87 HPGD (0.37) HPGDACHECHRNB2CHRNB4CHRNA3
SCHEMBL28876296 0.86 HPGD (0.43) HPGDACHECHRNB2CHRNB4CHRNA3
SCHEMBL28673557 0.78 CA12 (0.43) ACHEALDH1A1EPHX1ATM
SCHEMBL17415975 0.78 HPGD (0.43) HPGDACHEEPHX1
SCHEMBL28160030 0.76 CA12 (0.52) ACHEEPHX1
SCHEMBL11203544 0.76 ACHE (0.44) HPGDACHEEPHX1
SCHEMBL4349103 0.74
SCHEMBL4349098 0.74
SCHEMBL16935651 0.73 ACHE (0.34) ACHECHRNB2CHRNB4CHRNA3CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5389688-A Nonsolvent, aqueous emulsions comprising a water insoluble agriculture active materials, surfactants, alkyl pyrrolidones; nontoxic, stability, shelf life ISP INVESTMENTS INC. (US) 1995-02-14 US disclosed
US-5354726-A Hydrophilic and hydrophobic solvents prevent precipitation on extended storage ISP INVESTMENTS INC. (US) 1994-10-11 US disclosed
US-5283229-A A concentrate emulsions comprising an active materials, a surfactant and an amide solvent mixtures to dissolve, dispersing the water insoluble active materials; stability ISP INVESTMENTS INC. (US) 1994-02-01 US disclosed
US-5250499-A Delivery system for agricultural chemicals ISP INVESTMENTS INC. (US) 1993-10-05 US disclosed
US-5176736-A Emulsifiable herbicide concentrate ISP INVESTMENTS INC. (US) 1993-01-05 US disclosed
US-5160528-A Stable emulsifiable herbicide concentrates ISP INVESTMENTS INC. (US) 1992-11-03 US disclosed
US-5156666-A Emulsifiable concentrate comprising a pesticide, a surfactant, a hydrophobic solvent and a hydrophilic solvent; storage stability ISP INVESTMENTS INC. (US) 1992-10-20 US disclosed