Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 7/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 7/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555194 | 0.77 | CSNK1D (0.42) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL16204217 | 0.77 | PRMT1 (0.39) | CSNK1DCSNK1ETGFBR1MAPK1MEN1 | |
| SCHEMBL21753546 | 0.74 | CSF1R (0.45) | CSNK1DCSNK1EMAPK14TGFBR1ALDH1A1 | |
| SCHEMBL21753533 | 0.72 | CSNK1D (0.47) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL16201357 | 0.72 | KMT2A (0.40) | TGFBR1ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL29902525 | 0.71 | BTK (0.52) | CSNK1DCSNK1ETGFBR1BTK | |
| SCHEMBL1555110 | 0.70 | LPL (0.44) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL25237034 | 0.70 | LRRK2 (0.34) | — | |
| SCHEMBL23584998 | 0.70 | DRD2 (0.42) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 | |
| SCHEMBL20075127 | 0.69 | SLC34A1 (0.49) | CSNK1DCSNK1EMAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191884-A | Substituted 6- (1H-pyrazol-1-yl) pyrimidine-4-amine derivatives and uses thereof | 拜耳公司 | 2019-08-30 | — | — | CN | disclosed |