SCHEMBL28876579

SCHEMBL28876579

CN(C)Cc1cc(OC(N)=O)ncc1C1(O)CCOCC1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAP4K1 Q92918 1/20 0.38
CYP11B2 P19099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29736584 0.80 MAP4K1 (0.42) MAP4K1
SCHEMBL23089194 0.80 MAP4K1 (0.42) MAP4K1
SCHEMBL23089452 0.77 MAP4K1 (0.44) MAP4K1
SCHEMBL23106909 0.75 MAP4K1 (0.39) MAP4K1
SCHEMBL29736807 0.74 MAP4K1 (0.41) MAP4K1
SCHEMBL23104048 0.74 MAP4K1 (0.41) MAP4K1
SCHEMBL28876608 0.73 ALDH1A1 (0.35)
SCHEMBL28876524 0.68 CNR2 (0.34)
SCHEMBL23089165 0.61 HTR1D (0.36) MAP4K1
SCHEMBL29736697 0.61 HTR1D (0.36) MAP4K1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114945366-A HPK1 antagonists and uses thereof 林伯士萨顿公司 2022-08-26 CN disclosed