Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | NNMT | P40261 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23089103 | 0.82 | NNMT (0.31) | MEN1KMT2ANNMTSIRT6 | |
| SCHEMBL15881230 | 0.75 | NNMT (0.46) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL28898024 | 0.74 | NCOA1 (0.43) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL28876579 | 0.73 | MAP4K1 (0.38) | — | |
| SCHEMBL29150549 | 0.72 | PARP1 (0.31) | — | |
| SCHEMBL28898026 | 0.71 | SMN1; SMN2 (0.43) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL23089282 | 0.70 | GRM4 (0.35) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL27067135 | 0.70 | SLC6A2 (0.45) | ALDH1A1CYP2D6MEN1KMT2AKDM4E | |
| SCHEMBL23089073 | 0.70 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL29239402 | 0.70 | NCEH1 (0.31) | ALDH1A1CYP2D6MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945366-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2022-08-26 | — | — | CN | disclosed |