Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23089187 | 0.81 | HPGD (0.57) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL1684582 | 0.81 | HPGD (0.57) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL30173006 | 0.79 | HPGD (0.56) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL24992536 | 0.79 | HPGD (0.56) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL23089701 | 0.78 | HPGD (0.54) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL23089463 | 0.76 | HPGD (0.51) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL23089372 | 0.75 | ADORA2B (0.50) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19439102 | 0.74 | HPGD (0.57) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL19439103 | 0.73 | HPGD (0.77) | HPGDADORA2BADORA2AADORA1ADORA3 | |
| SCHEMBL23089545 | 0.72 | ADORA2B (0.47) | HPGDADORA2BADORA2AADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945366-A | HPK1 antagonists and uses thereof | 林伯士萨顿公司 | 2022-08-26 | — | — | CN | disclosed |