Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099593 | 1.00 | NR1H2 (0.30) | NR1H2 | |
| SCHEMBL27737962 | 0.92 | ENO1 (0.33) | — | |
| SCHEMBL28007510 | 0.91 | ENO1 (0.31) | — | |
| SCHEMBL30527152 | 0.88 | NR1H2 (0.33) | NR1H2 | |
| SCHEMBL27801904 | 0.83 | NR1H2 (0.30) | NR1H2 | |
| SCHEMBL28170317 | 0.83 | NCF1 (0.37) | NR1H2 | |
| SCHEMBL27907926 | 0.83 | NCF1 (0.37) | NR1H2 | |
| SCHEMBL27916742 | 0.83 | NCF1 (0.37) | NR1H2 | |
| SCHEMBL28128470 | 0.83 | NR1H2 (0.30) | NR1H2 | |
| SCHEMBL27972983 | 0.82 | AKR1C3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110325535-A | Piperidine-, morpholine-or piperazine-substituted [1,2,4] -triazolo [1,5-a ] -pyrimidinyl derivatives as OGA inhibitors | 詹森药业有限公司 | 2019-10-11 | — | — | CN | disclosed |
| CN-110312716-A | Bicyclic OGA inhibitor compound | 詹森药业有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110300752-A | Monocycle OGA inhibitor compound | 詹森药业有限公司 | 2019-10-01 | — | — | CN | disclosed |