Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 2/20 | 0.58 |
| ▸ | HTR2A | P28223 | 6/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.57 |
| ▸ | HRH1 | P35367 | 6/20 | 0.57 |
| ▸ | DRD3 | P35462 | 6/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.57 |
| ▸ | HTR6 | P50406 | 5/20 | 0.57 |
| ▸ | CACNA1C | Q13936 | 5/20 | 0.57 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.57 |
| ▸ | DRD4 | P21917 | 4/20 | 0.57 |
| ▸ | HRH2 | P25021 | 4/20 | 0.57 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.57 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.57 |
| ▸ | DRD5 | P21918 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210202 | 0.86 | SCN5A (0.57) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL7634586 | 0.83 | SCN5A (0.59) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL10334811 | 0.81 | SCN5A (0.58) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL28876807 | 0.81 | CYP3A4 (0.64) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL10362364 | 0.81 | HTR2A (0.61) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL2268114 | 0.81 | SIGMAR1 (0.58) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL11338768 | 0.81 | SIGMAR1 (0.58) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL10556025 | 0.81 | SCN5A (0.58) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| SCHEMBL4750789 | 0.81 | SLC6A3 (0.64) | SCN5AHTR2AADRA1AHRH1DRD3 | |
| Hydrochloric Acid SCHEMBL8627527 | 0.80 | MEN1 (0.58) | SCN5AHTR2AADRA1AHRH1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414421-B1 | 1-Oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1994-04-06 | — | — | EP | disclosed |
| US-5118687-A | Antihyporic agents, brain disorders | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-06-02 | — | — | US | disclosed |
| EP-0414421-A2 | 1-Oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-27 | — | — | EP | disclosed |