SCHEMBL28877284

SCHEMBL28877284

Fc1c(F)c(F)c2c(-c3cccs3)nncc2c1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.38
RPS6KB2 Q9UBS0 3/20 0.36
ADORA2A P29274 1/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2E1 P05181 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2A6 P11509 1/20 0.34
CYP2B6 P20813 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 1/20 0.34
KDM4E B2RXH2 4/20 0.33
HPGD P15428 2/20 0.33
POLB P06746 1/20 0.33
HTT P42858 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29947834 0.81 RPS6KB2 (0.43) ALDH1A1RPS6KB2ADORA2AMAPTKMT2A
SCHEMBL28877275 0.79 RPS6KB2 (0.39) ALDH1A1RPS6KB2ADORA2AMAPTKMT2A
SCHEMBL28957881 0.73 GABRA1 (0.36) ALDH1A1ADORA2ALMNAKDM4EHPGD
SCHEMBL28877245 0.73 ADORA1 (0.42) ALDH1A1RPS6KB2ADORA2AMAPTKMT2A
SCHEMBL28877299 0.71 SMN1; SMN2 (0.37) ALDH1A1RPS6KB2MAPTKMT2AMEN1
SCHEMBL28877247 0.70 ADORA2A (0.41) ALDH1A1ADORA2AMAPTKMT2AMEN1
SCHEMBL6240749 0.69 RPS6KB2 (0.50) ALDH1A1RPS6KB2ADORA2AMAPTKMT2A
SCHEMBL29352356 0.66 RPS6KB2 (0.46) ALDH1A1RPS6KB2ADORA2AMAPTKMT2A
SCHEMBL28466090 0.66 RPS6KB2 (0.54) ALDH1A1RPS6KB2ADORA2AMAPTKMT2A
SCHEMBL32670806 0.65 MEN1 (0.42) ALDH1A1RPS6KB2ADORA2AMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260245-A Iridium metal complex, application thereof and organic electroluminescent device 清华大学 2022-11-01 CN disclosed