Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29947834 | 0.87 | RPS6KB2 (0.43) | SMN1; SMN2MAPTKDM4ERPS6KB2NPSR1 | |
| SCHEMBL28877275 | 0.81 | RPS6KB2 (0.39) | SMN1; SMN2MAPTKDM4ERPS6KB2NPSR1 | |
| SCHEMBL28877245 | 0.78 | ADORA1 (0.42) | SMN1; SMN2MAPTKDM4ERPS6KB2NPSR1 | |
| SCHEMBL28877253 | 0.76 | KDM4E (0.38) | SMN1; SMN2MAPTKDM4EGAAALDH1A1 | |
| SCHEMBL28877247 | 0.75 | ADORA2A (0.41) | SMN1; SMN2MAPTKDM4EGAANPSR1 | |
| SCHEMBL28672805 | 0.75 | MAPT (0.39) | SMN1; SMN2MAPTKDM4ERPS6KB2GAA | |
| SCHEMBL29349648 | 0.75 | MAPT (0.39) | SMN1; SMN2MAPTKDM4ERPS6KB2GAA | |
| SCHEMBL28877328 | 0.74 | MAPT (0.40) | SMN1; SMN2MAPTNPSR1XBP1MEN1 | |
| SCHEMBL28673333 | 0.73 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTKDM4ERPS6KB2GAA | |
| SCHEMBL28877284 | 0.71 | ALDH1A1 (0.38) | SMN1; SMN2MAPTKDM4ERPS6KB2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260245-A | Iridium metal complex, application thereof and organic electroluminescent device | 清华大学 | 2022-11-01 | — | — | CN | disclosed |