Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877418 | 0.89 | LMNA (0.35) | ALDH1A1HSD17B10CASP1CASP7TDP1 | |
| SCHEMBL28877391 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CASP1CASP7TDP1 | |
| SCHEMBL28957895 | 0.87 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CASP1CASP7TDP1 | |
| SCHEMBL28877428 | 0.87 | AKR1C2 (0.39) | ALDH1A1HSD17B10TDP1AKR1C2AKR1C1 | |
| SCHEMBL28877369 | 0.82 | HSD17B10 (0.47) | ALDH1A1HSD17B10CASP1CASP7TDP1 | |
| SCHEMBL28877455 | 0.81 | HSD17B10 (0.46) | ALDH1A1HSD17B10CASP1CASP7TDP1 | |
| SCHEMBL28877438 | 0.71 | ALDH1A1 (0.39) | ALDH1A1HSD17B10CASP1CASP7TDP1 | |
| SCHEMBL23796737 | 0.70 | HSD17B10 (0.49) | ALDH1A1HSD17B10CASP1CASP7TDP1 | |
| SCHEMBL28877408 | 0.70 | ALDH1A1 (0.37) | ALDH1A1HSD17B10CASP1CASP7TDP1 | |
| SCHEMBL40170 | 0.69 | ALDH1A1 (0.48) | ALDH1A1LMNAMCL1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |