Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877448 | 0.87 | MEN1 (0.56) | GAAMEN1NPC1RAB9AKMT2A | |
| SCHEMBL23796738 | 0.83 | NR1H4 (0.64) | NR1H4MEN1KMT2ABCAT2HSD17B10 | |
| SCHEMBL23796683 | 0.82 | NR1H4 (0.50) | NR1H4GAAMEN1NPC1RAB9A | |
| SCHEMBL28877397 | 0.81 | GAA (0.48) | NR1H4GAAMEN1NPC1RAB9A | |
| SCHEMBL28877435 | 0.80 | TOP1 (0.47) | NR1H4GAAMEN1NPC1RAB9A | |
| SCHEMBL23796845 | 0.79 | KMT2A (0.57) | NR1H4MEN1KMT2AMAPTMAPK1 | |
| SCHEMBL23796297 | 0.79 | NR1H4 (0.47) | NR1H4MEN1NPC1RAB9AKMT2A | |
| SCHEMBL30032341 | 0.79 | NR1H4 (0.47) | NR1H4MEN1NPC1RAB9AKMT2A | |
| SCHEMBL23796278 | 0.78 | NR1H4 (0.49) | NR1H4KMT2APOLBMAPTBCAT2 | |
| SCHEMBL23796368 | 0.78 | AKR1C3 (0.52) | NR1H4MEN1KMT2APOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |