Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TOP1 | P11387 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877417 | 0.87 | NR1H4 (0.49) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL28877412 | 0.83 | KMT2A (0.55) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL23796661 | 0.82 | NR1H4 (0.56) | BCAT2TERT | |
| SCHEMBL28877435 | 0.81 | TOP1 (0.47) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL23796556 | 0.81 | KMT2A (0.51) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL30031454 | 0.81 | KMT2A (0.51) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL28877426 | 0.79 | KMT2A (0.56) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL23796744 | 0.78 | BCAT2 (0.46) | MEN1KMT2ABCAT2P2RX1TERT | |
| SCHEMBL30032398 | 0.78 | BCAT2 (0.46) | MEN1KMT2ABCAT2P2RX1TERT | |
| SCHEMBL9155636 | 0.77 | MEN1 (0.68) | MEN1KMT2ANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |