Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877413 | 0.86 | TOP1 (0.48) | TOP1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL28877392 | 0.82 | TOP1 (0.44) | TOP1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL23796532 | 0.82 | LMNA (0.45) | TOP1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL30031668 | 0.82 | LMNA (0.45) | TOP1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL23796458 | 0.81 | CA1 (0.45) | MAPTKMT2ALMNAALDH1A1CA1 | |
| SCHEMBL30031321 | 0.81 | CA1 (0.45) | MAPTKMT2ALMNAALDH1A1CA1 | |
| SCHEMBL28877404 | 0.78 | TOP1 (0.49) | TOP1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL28957929 | 0.75 | TOP1 (0.44) | TOP1MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL23796620 | 0.75 | NR1H4 (0.43) | LMNACA1CA2CA9NPC1 | |
| SCHEMBL30032625 | 0.75 | NR1H4 (0.43) | LMNACA1CA2CA9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |