Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | FADS1 | O60427 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877472 | 0.83 | KMT2A (0.46) | TOP1KMT2AATMRXFP1MEN1 | |
| SCHEMBL23796466 | 0.81 | ALDH1A1 (0.51) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL30031069 | 0.81 | ALDH1A1 (0.51) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL30031941 | 0.80 | P2RX1 (0.49) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL23796782 | 0.80 | P2RX1 (0.49) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL12519866 | 0.78 | RAB9A (0.60) | KMT2AP2RX1MEN1MAPTHTT | |
| SCHEMBL28877460 | 0.78 | TOP1 (0.48) | TOP1KMT2ACA12CA1CA2 | |
| SCHEMBL28877426 | 0.77 | KMT2A (0.56) | TOP1KMT2ACA2P2RX1MEN1 | |
| SCHEMBL23796744 | 0.75 | BCAT2 (0.46) | KMT2ACA12CA1CA2CA9 | |
| SCHEMBL30032398 | 0.75 | BCAT2 (0.46) | KMT2ACA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |