Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877369 | 0.88 | HSD17B10 (0.47) | HSD17B10LMNAHIF1AHPGDPGAM1 | |
| SCHEMBL28877386 | 0.84 | HSD17B10 (0.40) | HSD17B10LMNAHIF1AHPGDCASP1 | |
| SCHEMBL28877418 | 0.77 | LMNA (0.35) | HSD17B10LMNAHIF1AHPGDPGAM1 | |
| SCHEMBL28877445 | 0.77 | HSD17B10 (0.35) | HSD17B10LMNAHIF1AHPGDPGAM1 | |
| SCHEMBL3235461 | 0.76 | HSD17B10 (0.45) | HSD17B10LMNAHIF1AHPGDPGAM1 | |
| SCHEMBL28877429 | 0.75 | HSD17B10 (0.40) | HSD17B10LMNAHIF1AHPGDCASP1 | |
| SCHEMBL8009755 | 0.74 | HSD17B10 (0.44) | HSD17B10LMNAHIF1AHPGDPGAM1 | |
| SCHEMBL3197344 | 0.74 | HSD17B10 (0.44) | HSD17B10LMNAHIF1AHPGDPGAM1 | |
| SCHEMBL28877408 | 0.74 | ALDH1A1 (0.37) | HSD17B10LMNAHPGDCASP1CASP7 | |
| SCHEMBL8365873 | 0.73 | TYR (0.45) | HSD17B10LMNAHIF1AHPGDPGAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |