Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RGS12 | O14924 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28877433 | 0.86 | PTGS2 (0.39) | POLBHPGDTDP1MAPTKDM4E | |
| SCHEMBL30032060 | 0.84 | ALOX15 (0.42) | POLBHPGDTDP1MAPTKDM4E | |
| SCHEMBL28877376 | 0.84 | ALOX15 (0.42) | POLBHPGDTDP1MAPTKDM4E | |
| SCHEMBL28877524 | 0.82 | KDM4E (0.40) | POLBHPGDTDP1MAPTKDM4E | |
| SCHEMBL28877427 | 0.76 | LCK (0.43) | POLBHPGDTDP1MAPTKDM4E | |
| SCHEMBL23796741 | 0.74 | KDM4E (0.47) | POLBHPGDTDP1MAPTKDM4E | |
| SCHEMBL30031102 | 0.74 | KDM4E (0.47) | POLBHPGDTDP1MAPTKDM4E | |
| SCHEMBL28877442 | 0.70 | POLB (0.42) | POLBMAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL30031472 | 0.70 | POLB (0.42) | POLBMAPTKDM4EHSD17B10MEN1 | |
| SCHEMBL6905494 | 0.70 | KDM4E (0.43) | POLBHPGDTDP1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |