Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263495 | 0.77 | ERN1 (0.37) | ERN1MAPT | |
| SCHEMBL28171587 | 0.74 | HTR2C (0.43) | HTR2CKIF11MAPT | |
| SCHEMBL21625594 | 0.73 | PTPN1 (0.37) | ERN1 | |
| SCHEMBL4097626 | 0.73 | ERN1 (0.44) | ERN1 | |
| SCHEMBL5987754 | 0.73 | HTR2C (0.43) | HTR2CMAPT | |
| SCHEMBL24339440 | 0.73 | ALDH1A1 (0.38) | ERN1MAPT | |
| SCHEMBL6335072 | 0.72 | HTR2C (0.46) | HTR2CMAPT | |
| SCHEMBL28878093 | 0.71 | XDH (0.43) | HTR2C | |
| SCHEMBL29967294 | 0.71 | XDH (0.43) | HTR2C | |
| SCHEMBL3245477 | 0.71 | PIM1 (0.42) | ERN1PIM1PIM3KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260180-B | Triazole condensed ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260180-A | Triazole fused ring containing derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-01 | — | — | CN | disclosed |