Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2768950 | 0.78 | FKBP1A (0.54) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL31380064 | 0.75 | MAPT (0.53) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL31380063 | 0.75 | MAPT (0.53) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL17068139 | 0.75 | POLB (0.48) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL20612845 | 0.75 | POLB (0.48) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL18045339 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL2478514 | 0.74 | FKBP1A (0.46) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| SCHEMBL29561442 | 0.74 | ALDH1A1 (0.45) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL10692531 | 0.74 | GBA1 (0.53) | ALDH1A1MAPTHPGDNPSR1HSD17B10 | |
| Hydrochloric Acid SCHEMBL6951430 | 0.74 | GBA1 (0.53) | ALDH1A1MAPTHPGDNPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260180-B | Triazole condensed ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-115260180-A | Triazole fused ring containing derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-11-01 | — | — | CN | disclosed |