Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28878297 | 1.00 | GPR119 (0.45) | GPR119PTPN2PTPN1PTPN6FPR2 | |
| SCHEMBL26695711 | 0.83 | MAOB (0.50) | GPR119PTPN2PTPN1PTPN6FPR2 | |
| SCHEMBL14261797 | 0.83 | MAOB (0.50) | GPR119PTPN2PTPN1PTPN6FPR2 | |
| SCHEMBL20015680 | 0.83 | MAOB (0.50) | GPR119PTPN2PTPN1PTPN6FPR2 | |
| SCHEMBL20015325 | 0.81 | GPR119 (0.60) | GPR119 | |
| SCHEMBL28329047 | 0.79 | USP30 (0.60) | GPR119 | |
| SCHEMBL28329049 | 0.79 | USP30 (0.60) | GPR119 | |
| SCHEMBL14720686 | 0.79 | GRM5 (0.47) | GPR119 | |
| SCHEMBL3060853 | 0.79 | GPR119 (0.48) | GPR119PTPN2PTPN1PTPN6FPR2 | |
| SCHEMBL31697735 | 0.79 | GPR119 (0.48) | GPR119PTPN2PTPN1PTPN6FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110506044-B | BRD4 inhibitor and preparation and application thereof | 中国科学院上海药物研究所 | 2022-07-05 | — | — | CN | disclosed |
| CN-110506044-A | A kind of BRD4 inhibitor and its preparation and application | SHANGHAI INST MATERIA MEDICA CAS | 2019-11-26 | — | — | CN | disclosed |