Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | RAB9A | P51151 | 7/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.61 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.61 |
| ▸ | CASP3 | P42574 | 9/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 9/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 8/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 8/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29974383 | 1.00 | NPC1 (0.66) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12393158 | 0.83 | MEN1 (0.70) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL29974198 | 0.80 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL28878457 | 0.80 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL29974715 | 0.80 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL28878446 | 0.80 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL2116067 | 0.79 | MEN1 (1.00) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL12368479 | 0.79 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL334252 | 0.78 | NPC1 (0.61) | NPC1RAB9ASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL11279344 | 0.76 | DYRK1A (1.00) | NPC1RAB9ASMN1; SMN2HTTDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151536-A | Antiviral compounds, compositions and methods of use | 不列颠哥伦比亚大学 | 2022-10-04 | — | — | CN | disclosed |