Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 3/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639542 | 0.83 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL780242 | 0.82 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2172323 | 0.82 | ALDH1A1 (0.46) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9307123 | 0.81 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL617735 | 0.81 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10575044 | 0.81 | KMT2A (0.51) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL141868 | 0.81 | RAB9A (0.51) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL369617 | 0.81 | KMT2A (0.51) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL369984 | 0.81 | GFER (0.61) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL779483 | 0.81 | HTT (0.61) | KMT2AMAPTGAAHTTAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 571 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045993-A | Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof | 西南交通大学 | 2021-06-29 | — | — | CN | claimed |
| US-10655015-B2 | Tire crumb-based bitumen polymer for producing a lower viscosity asphalt with improved tolerance to high temperatures | Argopro Group LLC (US) | 2020-05-19 | — | — | US | claimed |
| US-20200095424-A1 | TIRE CRUMB-BASED BITUMEN POLYMER FOR PRODUCING A LOWER VISCOSITY ASPHALT WITH IMPROVED TOLERANCE TO HIGH TEMPERATURES | Argopro Group LLC | 2020-03-26 | — | — | US | claimed |
| CN-105524268-B | Sulfonated polyether ketone copolymers of the group containing benzothiazole and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2017-09-15 | — | — | CN | claimed |
| EP-0266662-B1 | PROCESS FOR THE PREPARATION OF POLY(ARYLENSULPHIDES) WITH LOWER CRYSTALLIZATION TEMPERATURE | BAYER AG (DE) | 1992-06-10 | — | — | EP | claimed |
| US-4824933-A | DIMENSIONAL STABILITY, CHEMICAL RESISTANT | BAYER AKTIENGESELLSCHAFT (DE) | 1989-04-25 | — | — | US | claimed |
| US-4433153-A | Process for the manufacture of 2,6-dichlorobenzoxazole and 2,6-dichlorobenzthiazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-21 | — | — | US | claimed |
| EP-0098957-A2 | Process for preparing crystalline 2,6-dichlorobenzothiazole | CASSELLA Aktiengesellschaft (DE) | 1984-01-25 | — | — | EP | claimed |
| EP-0043573-B1 | PROCESS FOR THE PREPARATION OF 2,6-DICHLOROBENZOXAZOLE OR 2,6-DICHLOROBENZTHIAZOLE | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-08-31 | — | — | EP | claimed |
| EP-0043573-A1 | Process for the preparation of 2,6-dichlorobenzoxazole or 2,6-dichlorobenzthiazole | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-13 | — | — | EP | claimed |
| CN-117120423-B | Indolylamine 2, 3-dioxygenase inhibitors, methods of preparing the same, and pharmaceutical compositions containing the same | 柳韩洋行 | 2026-02-27 | — | — | CN | disclosed |
| EP-4631938-A1 | NITROGEN-CONTAINING HETEROCYCLE WITH SEROTONIN RECEPTOR-BINDING ACTIVITY AND CARBOCYCLIC DERIVATIVE | Shionogi & Co., Ltd (JP) | 2025-10-15 | — | — | EP | disclosed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| CN-119548987-A | Nanofiltration membrane preparation method, nanofiltration membrane prepared by method and application of nanofiltration membrane | 沃顿科技股份有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-112703192-B | Compound and organic light emitting device comprising the same | 株式会社LG化学 | 2025-02-07 | — | — | CN | disclosed |
| EP-0039905-A1 | Process for the preparation of 2-chloro-benzothiazole | CASSELLA Aktiengesellschaft (DE) | 1981-11-18 | — | — | EP | disclosed |
| EP-0039440-A1 | Medicines containing substituted benzothiazol-2-(3H)-ones | Dr. Karl Thomae GmbH (DE) | 1981-11-11 | — | — | EP | disclosed |
| EP-0000924-B1 | HETEROCYCLIC PHENYL ETHERS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-29 | — | — | EP | disclosed |
| US-4263440-A | STARTING MATERIALS FOR HERBICIDE PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-04-21 | — | — | US | disclosed |
| EP-0000924-A1 | Heterocyclic phenyl ethers and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | NPC1 1202/4885RAB9A 2680/4885SMN1; SMN2 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.