Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 6/20 | 0.38 |
| ▸ | PPARD | Q03181 | 6/20 | 0.38 |
| ▸ | PPARA | Q07869 | 6/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.38 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27518989 | 0.81 | CA4 (0.50) | TDP1BLM | |
| Adipic Acid SCHEMBL28332289 | 0.80 | LMNA (0.50) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL4637032 | 0.80 | LMNA (0.50) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| Adipic Acid SCHEMBL1408901 | 0.78 | LMNA (0.69) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| Adipic Acid SCHEMBL1408899 | 0.78 | LMNA (0.69) | LMNATSHRNFKB1PMP22ALDH1A1 | |
| SCHEMBL27637160 | 0.78 | CA4 (0.53) | TDP1BLM | |
| SCHEMBL28105310 | 0.78 | CA4 (0.53) | TDP1BLM | |
| Ammonia Solution, Strong SCHEMBL28204706 | 0.78 | CA4 (0.53) | TDP1BLM | |
| SCHEMBL28806771 | 0.78 | CA4 (0.53) | TDP1BLM | |
| SCHEMBL8375010 | 0.78 | CA4 (0.53) | TDP1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110367268-A | A kind of regulation composition and its application for citrus flower and fruit protecting | 江西新瑞丰生化股份有限公司 | 2019-10-25 | — | — | CN | disclosed |